Ono-rs-082
WebKey features and details. Potent, reversible phospholipase A 2 (PLA 2) inhibitor. CAS Number: 99754-06-0. Purity: > 98%. Soluble in DMSO to 50 mM (with warming) and in … WebProduct Description. ONO-RS-082 is a reversible inhibitor of Ca 2+ -independent phospholipase A 2. 1 At 3.5 µM, it has been shown to inhibit epinephrine-stimulated …
Ono-rs-082
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WebThe PLA2 inhibitors ONO-RS-082 (2-[p-amylcinnamoyl] amino-4-chlorobenzoic acid, C HCINO ; hereafter ONO; Figure ' 21 22 3' ' O 1A, inset) and bromoenol lactones (haloenol lactone suicide substrate [HELSS], bromoenol lactone) can induce Golgi frag mentation and inhibit membrane trafficking and BFA-induced WebONO-RS-082, 98% Shop Thermo Scientific™ ONO-RS-082, 98% at Fishersci.com. English English; Change Country. Get All The Latest News Help & Support Center › English …
WebBoth uptake activity and efflux are inhibited by ACA. Other Na(+)/dicarboxylate transporters from the SLC13 family, including hNaDC3 and rbNaDC1, were also inhibited by ACA, ONO-RS-082, and Fmoc-anthranilic acid, whereas the Na(+)/citrate transporter (hNaCT) is much less sensitive to these compounds. WebONO-RS-082 Phospholipase inhibitor Replaces Prod. #: ALX-270-115 Phospholipase A2inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose.
WebCells were pretreated for 16 h with ONO-RS-082 (2.5 µM) and further treated for 48 h with doxorubicin (4.7 nM in SRB and 20 nM in Annexin-V-FITC). WebIt was also found that lipocortin I and ONO-RS-082, but not neomycin, facilitated the generation of GIF-producing T cells. When spleen cells of ovalbumin (OVA)-primed BDF1 mice were stimulated with homologous antigen and the activated T cells were propagated by recombinant IL-2 in the presence of GIF, lipocortin I, or ONO-RS-082, T cells obtained in …
WebONO-RS-082 is a reversible inhibitor of Ca2+-independent phospholipase A2. Phospholipases A2 (PLA2s) are enzymes releasing fatty acids from the second carbon …
WebApplication: ONO-RS-082 is a potent PLA2 and epinephrine inhibitor. CAS Number: 99754-06-0. Purity: ≥98%. Molecular Weight: 371.86. Molecular Formula: C 21 H 22 ClNO 3. … population action internationalWebCulture of the 12H5 cells either with nonspecific glycosylation Inhibiting factor (GIF) or with a phospholipase A2 (PLA2) inhibitor, ONO-RS-082, stopped the formation of GEF and Induced the same cells to form GIF. shark songs on youtubeWeb19 de jan. de 2024 · ONO-RS-082 (10 μM) prevents P. aeruginosa strain PAO1-induced polymorphonumclear cells (PMNs) transepithelial migration, demonstrating that PLA2 … population achenheimWeb20 de nov. de 2009 · For example, during treatment of cells with the reversible antagonist ONO-RS-082, the Golgi complex fragments into smaller “mini-stacks.” Upon washout, Golgi membranes rapidly form extensive membrane tubules that mediate the coalescence of the mini-stacks into an intact Golgi ribbon (de Figueiredo et al., 1999; Judson & Brown, 2009). population above 18 years in indiaWeb4- (Hydroxymercuri)benzoic acid sodium salt. Synonym (s): p-Chloromercuribenzoate, p-Hydroxymercuribenzoic acid sodium salt, PCMB, Sodium 4- (hydroxymercurio)benzoate. Empirical Formula (Hill Notation): C7H5HgNaO3. CAS No.: population abundance vs densityWebONO-RS-082 (2-(p-Amylcinnamoyl)amino-4-chlorobenzoic acid );≥97% HPLC; This compound is also offered as part of Sigma′s Library of Pharmacologically Active … population action international bankWebHere, we investigate the antibiotic properties of a compound, ONO-RS-082 (ONO), which was identified by bacterial cytological profiling as operating via a novel MoA. We found … population action international jobs